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Reported EC values for MT-II in transfected cell assays fall in the sub-nanomolar to low-nanomolar range at MC1R and MC4R, roughly an order of magnitude weaker at MC3R and MC5R, and it is essentially inactive at MC2R, the adrenocorticotropin receptor

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Availability and FDA approval status This is perhaps the most practically important section of the entire comparison

You might wonder if a morning dose will give you the appetite control you need for the day or if a nighttime dose will help you sleep through the most common side effects