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doi: 10.1136/thorax.55.4.266 62 SiddiqiH
These medicines work by mimicking the action of the naturally occurring hormone GLP-1, which stimulates insulin secretion, suppresses glucagon release, and slows gastric emptying
Drug Deliv Transl Res 11:22242238
Bypasses upstream endocrine stimulation: Unlike peptides that stimulate growth hormone release, IGF-1 LR3 does not depend on pituitary activation
Both remain classified as research compounds, and all published data comes from preclinical and animal studies rather than human clinical trials
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