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Exendin-4 is a peptide agonist of the GLP-1 receptor that promotes insulin secretion
The accelerated approval requires confirmatory evidence from the ESSENCE trial and other ongoing studies to validate long-term clinical benefit.
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If you need B12 injections as part of treatment for a B12 deficiency, we may be able to prescribe a B12 injection for you if you can provide adequate proof of this, and consent to us informing your regular healthcare provider of the injections
However, the incidence of gallbladder disease, even after factoring for the degree of weight loss, was greater in semaglutide patients than in placebo
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