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Potential ROS induction pathways include the NF-B, mitogen-activated protein kinase, phosphoinositide 3-kinaseAkt, and Keap1Nrf2ARE signaling pathways 39

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Phase Mid escalation Weeks 9-12 Weekly Dose 6 mg Notes Watch GI side effects

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Hama S, Takahashi K, Inai Y, Shiota K, Sakamoto R, Yamada A, Tsuchiya H, Kanamura K, Yamashita E, Kogure K (2012a) Protective effects of topical application of a poorly soluble antioxidant astaxanthin liposomal formulation on ultraviolet induced skin damage

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