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Nrf2ekeap1 system versus NF-kB: The good and the evil in chronic kidney disease

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BPC-157 is a 15-residue, 1419.53 g/mol pentadecapeptide whose mechanistic literature centres on local angiogenic signalling, Hsieh and colleagues (J Mol Med, 2017) reported upregulation and internalisation of VEGFR2 in human endothelial cells, and Chang and colleagues (J Appl Physiol, 2011) reported increased FAK and paxillin phosphorylation with greater outgrowth and migration in cultured rat tendon fibroblasts

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doi: 10.1016/j.redox.2021.101930 305 ZhangQ.XiangR.HuoS.ZhouY.JiangS.WangQ.et al