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The vitamin D RDA is 600 IU/day for adults up to 70 and 800 IU/day above 70, with a tolerable upper limit of 4,000 IU (NIH Office of Dietary Supplements)
May provide additional metabolic benefits, including improved beta-cell function, reduced glucagon secretion, delayed gastric emptying, and increased satiety 22
The FDA-approved labeling for GLP-1 medications lists gastrointestinal symptoms as the most frequent adverse reactions, but comprehensive tracking should capture the full spectrum of potential effects
Unmanaged free radicals damage lipids, proteins, and DNA, leading to cellular dysfunction
Klausen M, Justesen S, Pedersen J et al.Once-weekly semaglutide versus placebo in patients with alcohol use disorder and comorbid obesity: a randomised, double-blind, placebo-controlled trialThe Lancet, 407, 1687-1698 Herman, Rae J
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