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Very approximately, therapeutic antioxidant strategies can be classified as (i) application of low molecular weight antioxidants and vitamins including activators of Nuclear factor erythroid 2related factor 2 (Nrf2), playing an important role in the expression of antioxidant enzymes and (ii) targeting ROS with antioxidant enzymes involving SOD mimetics or NOX inhibitors (Batinic-Haberle et al
May modulate energy metabolism under stress conditions
Key takeaways Vitamin B12 deficiency can cause headaches and may be linked to chronic migraine
Nitric oxide modulates the expression of endothelial cell adhesion molecules involved in angiogenesis and leukocyte recruitment
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