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Thirteen had usable data in the anterior cingulate cortex (ACC), 10 had usable data in the left dorsolateral prefrontal cortex (DLPFC)
suggested that TMAO is not a toxic molecule of cardiovascular disease, rather its metabolic precursor TMA is (19, 20)
Furthermore, peripheral nerve injury leads to neuropathic pain, and the spared nerve injury (SNI) model in mice induces persistent heat hyperalgesia 44
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The male-to-female ratio was 1.56:1, suggesting a slight male prevalence of the disease
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