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Microbiota-derived metabolites represent a plausible mechanistic interface: SCFAs and secondary bile acids can strengthen epithelial barrier function, modulate host metabolism via FXR- and TGR5-dependent signaling, and attenuate low-grade inflammation, potentially reinforcing pharmacologically targeted pathways

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Sterile solution water is safer when only one dose is required for immediate use

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#CVD Risk: Manage aggressively, as cardiovascular disease remains the leading cause of death in MASLD patients