semaglutide or tirzepatide better vs. Tirzepatide: What's the Difference and Which Is Right for You?: Envizion Medical: Wellness Center Semaglutide vs Tirzepatide: 2026 Comparison

Berry RB, Kouchi K, Bower J, Prosise G, Light RW

If progress stalls, discussing dose adjustment with your provider becomes appropriate

Eli Lilly reported its first Phase 3 readout (TRIUMPH-4) in December 2025, showing about 28.7% weight loss at 68 weeks, and a larger pivotal trial (TRIUMPH-1) in May 2026 showing about 28.3% weight loss at 80 weeks in 2,339 participants

So its difficult to say currently if these injections have a durational maximum

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