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Primary hippocampal neuron cultures are used to study Dihexa's proposed effects on dendritic spine density and synaptic protein expression, typically measuring morphological changes via fluorescence microscopy and quantifying synaptic marker expression (such as PSD-95 or synaptophysin) relative to untreated controls
Low hypoglycaemia risk: Because GLP-1 medications only stimulate insulin release when glucose levels are elevated, the risk of low blood sugar is low unless they are combined with insulin or sulfonylurea medications
R., Chasan-Taber, L., Albright, A
For a deeper walk-through of managing the common early effects, see our guide on GLP-1 side effect management
Several such experiments are summarized in % of pre-drug value (Fig
