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In addition, GLP-1RA can not only inhibit the PI3K/Akt signaling pathway after activating GLP-1R (13) but also downregulate the expression levels of Cyclin A2 and Cyclin D1,which are markers of cell proliferation related to downstream pathways (95)

There were no cases of severe hypoglycemia or glycemic rescue

Furthermore, the expression of Brain-Derived Neurotrophic factor (BDNF) is enhanced, which is essential for the proper functioning of brain neurons (22)

K., Erlandson, K

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