glutathione and ckd deficiency alters the vitamin D-metabolizing enzymes CYP27B1 CYP24A1 in human renal proximal tubule epithelial cells and kidney of HFD-fed mice subq glutathione effects on kidneys

Others remain experimental, have only been studied in animals or laboratories, or have very limited safety data in humans

Int J Res Rev 9:308317 Park HJ, Lee YJ, Ryu HK, Kim MH, Chung HW, Kim WY (2008) A randomized double-blind, placebo-controlled study to establish the effects of spirulina in elderly Koreans

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A phase I safety study in healthy adults confirmed that subcutaneous MOTS-c injections at doses up to 10 mg produced no serious adverse events, with a pharmacokinetic profile supporting once-daily or every-other-day dosing [3]