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However, thats not the only reason

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Without treatment, Lyme disease can progress to Lyme arthritis, causing severe joint swelling, particularly in the knees

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Algunos pacientes pueden alcanzar sus objetivos teraputicos con dosis submximas y experimentar menos efectos secundarios, mientras que otros pueden requerir y tolerar dosis mximas para obtener beneficios ptimos

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Importantly, it does not typically drive insulin release under low-glucose conditions, reducing hypoglycemia risk in research settings

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Other important adverse effects include acute pancreatitis (presenting as severe, persistent abdominal pain radiating to the back), gallbladder disease , and acute kidney injury , particularly in the context of severe gastrointestinal side effects leading to dehydration

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