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[3] [4] If severe gastrointestinal symptoms occur, the bioavailability of bupropion might be temporarily reduced

Alternative pain management approaches should be considered: Topical NSAIDs gels or creams applied directly to painful areas (e.g., ibuprofen gel for muscle strains) provide localised relief with minimal systemic absorption Physical therapies heat or cold application, gentle exercise, physiotherapy Prescription alternatives your GP may recommend other analgesics depending on pain type and severity For specific pain types , tailored approaches work best

Our body ages and ceases to perform optimally

Supplementary material The Supplementary Material for this article can be found online at: References 1 NevotsCNisiorESabatJ-M

Do not take two doses at the same time to avoid problems