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Routine monitoring of serum calcitonin or using thyroid ultrasound is of uncertain value for early detection of MTC in patients treated with MOUNJARO

These results are not marginala 5-8 percentage point difference translates to meaningful additional fat loss and metabolic improvement for many patients

Instead of focusing on restrictions, GPs can encourage patients to focus on habits that nurture gut and metabolic health: Fibre-rich foods (whole grains, legumes, vegetables): promote bowel regularity and microbial diversity Hydration: supports constipation management and reduces nausea Nutrient-dense, whole foods: prioritise quality over quantity, especially when appetite is low GLP-1 receptor agonists provide a unique window to build lasting healthy habits

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Even in healthy adults, the GI burden is real and the long-term unknowns remain