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People on anticoagulant therapy need medical clearance before using any compound that affects vascular function

animal testing results arent accepted.6 The NEA requires three types of safety testing: the Human Repeat Insult Patch Test (HRIPT), Safety in Use (SIU), and the Cumulative Irritation Test (CIT)

These neuroprotective effects may contribute to improved mood and behavior by preserving and optimizing brain function

Perhaps they were imprecise and unsuccessful

It is also used to treat pernicious anemia, vitamin B 12 deficiency (due to low intake from food or inability to absorb due to genetic or other factors), thyrotoxicosis, hemorrhage, malignancy, liver disease and kidney disease