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Some disorders of intracellular cobalamin metabolism (cblC, cblD-MMA/Hcy, cblF, and cblJ) do not only compromise the synthesis of methylcobalamin, but also the synthesis of adenosylcobalamin, cofactor of the enzyme methylmalonyl-CoA mutase, leading to elevated concentrations of both tHcy and methylmalonic acid (MMA)

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For example, a study conducted by Hsieh et al

Pernicious Anemia Pernicious anemia is an autoimmune condition in which the body attacks the cells that produce intrinsic factor

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