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Brain serotonin, carbohydrate-craving, obesity and depression
J Cutan Pathol 41(1):6365
One burns what's there, the other changes the trajectory, burning fat instead of storing it
Compelling preclinical rationale, early adopter enthusiasm, and a safety evidence base that wouldn't survive FDA scrutiny
Abbreviations BMI: Body mass index DPP-4is: Dipeptidyl peptidase-4 inhibitors GLP-1 RAs: Glucagon-like peptide-1 receptor agonists HbA1c: Hemoglobin Alc ICERs: Incremental cost-effectiveness ratios PSA: Probabilistic sensitivity analyses QALYs: Quality-adjusted life years SBP: Systolic blood pressure SMPA: Sunshine Medical Procurement All-In-One UKPDS: United Kingdom Prospective Diabetes Studies References International Diabetes Federation
