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However, it is unclear which of these, the size increase or HSA binding, are more pharmacologically relevant and account for the observed extension of the half-life

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Indeed, GLP-1 RAs may support the preservation of muscle mass and function through improvements in glycemic control, weight reduction, and indirect modulation of inflammatory responses [81]

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It increases insulin secretion when blood sugar is elevated, slows gastric emptying so you feel full longer, and activates satiety centers in the hypothalamus

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