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Increased nitric oxide activity has also been demonstrated in resistance trained persons with reactive hyperaemia testing, an assessment used in clinical settings that, to some degree, simulates the physical stresses encountered during very intense exercise such as resistance training [7]

Data availability Data supporting the findings of this study are available in the article, its Supplementary information, the Source Data file and from the corresponding authors upon request

Those who experience a B12 deficiency due to issues absorbing B12 Aside from the typical symptoms of B12 deficiency, developing more serious or long-lasting complications is possible

All mouse experimental procedures were approved by the Animal Ethics Committee of Qingdao Agricultural University (approval number: 2022-0021)

The siRNA targeting MALAT1 (si-MALAT1) and its negative control (si-NC), as well as the miR-155-5p inhibitor and its corresponding control (Ctrl inhibitor), were designed and synthesized by GenePharma (Suzhou, China)