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The data isn't bulletproof (preparation methods vary, study quality is uneven), but it's further along than BPC-157's primarily animal evidence base

The mechanism is genuinely interesting and multi-pathway, but several steps remain incompletely characterized: Growth hormone receptor pathway: Animal studies from the Sikiric group show BPC-157 upregulates GH receptor expression in tendon fibroblasts, which may amplify local anabolic signaling without raising systemic GH or IGF-1 levels

Older adults often produce less stomach acid, which is necessary to release B12 from food