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It contains structural changes that extend its half-life and reduce binding to IGF-binding proteins, allowing it to remain active in circulation longer than endogenous IGF-1

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Indian J Pharmacol 34(5):365366 Szumny D et al (2024) Extract from Aronia melanocarpa , Lonicera caerulea , and Vaccinium myrtillus improves near visual acuity in people with presbyopia

doi:10.3390/ijms23052717 Bigio B, Azam S, Math AA, Nasca C