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Retatrutide (LY3437943 40 mg) GLP-1 + GIP + Eli Lilly
It is important to note that GLP-1 agonists are not for everyone
The phase 2 signal that put retatrutide on the map The pivotal early evidence is the phase 2 trial published in the New England Journal of Medicine in 2023, which randomized 338 adults with obesity to escalating retatrutide doses or placebo over 48 weeks
Research chemical semaglutide can cost a fraction of these prices, sometimes $50-100 for a multi-month supply at common dosing levels