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2ac and Supplemental Table 3)
Phase II methylation of estrogen requires the COMT enzyme (catechol oxygen methyltransferase)
However, if your doctor has directed you to take low-dose aspirin for heart attack or stroke prevention (usually at dosages of 81-325 milligrams a day), you should continue taking it unless your doctor instructs you otherwise
The gradual nature of micro-dosing benefits from extended consistent application
Krug et al., 2019)
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