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And its not true
Although GLP-1RAs seem to have a beneficial influence in reversing many maladaptive brain changes relevant to depression, it should be remembered that at the same time, they are also known to mediate some unfavorable processes such as activation of the HPA axis and intensification of anxiety-like behavior in some animal studies
However, if you have been at maximum dose for 12 or more weeks without adequate response, or if side effects prevent further dose increases, switching to tirzepatide is a reasonable next step
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Excess weight can negatively impact ones physical and emotional well-being and can lead to an increased risk of developing metabolic syndrome, cardiovascular health issues, insulin resistance, and type 2 diabetes
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