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Indeed, by comparing the high-dose liraglutide therapy (3.0 mg/day) with the combination therapy (metformin 1000 mg BID + liraglutide 1.2 mg/day), Jensterle et al
doi:10.1056/nejmoa2500969 7.Wharton S, Aronne LJ, Stefanski A, et al
Negatively charged nucleic acids do not easily cross the negatively charged lipid bilayer of the cell membrane
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