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Astrocytes release free fatty acids (FFAs) from lipid droplets, and the released fatty acids enter the mitochondria and bind to carnitine to form LCACs, the accumulation of which leads to mitochondrial dysfunction in astrocytes and exacerbates neuronal damage [115]
Furthermore, the potent antioxidant capacity of ascorbate can cause Fe 3+ to change into Fe 2+ via Fentons reaction
RESULTS This nationwide cohort study evaluated the IRRs associated with cancer development in patients with T2DM treated with GLP-1 RAs in South Korea
A.IsgroveK.et al (2018)
Elucidating these inhibitory signals is vital for a comprehensive understanding of the crosstalk between ferroptosis and macrophages
