t-Darpp activates IGF-1R/AKT signaling through heterodimerization with EGFR and HER2, promoting and stimulating glucose uptake, glycolysis and trastuzumab resistance in SK-BR-3 cells
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In HCC, Luo et al
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doi: 10.3389/fendo.2026.1805015 Received 05 February 2026 Revised 06 March 2026 Accepted 12 March 2026 Published 26 March 2026 Volume 17 - 2026 Edited by Yuzuru Ohshiro, Omoromachi Medical Center, Japan Reviewed by Edward Wargent, University of Buckingham, United Kingdom Antonio Maria Labate, ASST Franciacorta, Italy Updates Copyright 2026 Alkhezi, Alfehaid, Alanezi, Alotaibi and Alshaya