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Key mechanisms identified in published laboratory research include: Copper chaperone activity: This compound acts as a copper transport molecule in research models, delivering Cu(II) ions to copper-dependent enzymes, including lysyl oxidase (involved in collagen and elastin crosslinking) and superoxide dismutase (a key antioxidant enzyme)

NICE appraisals are based on robust clinical evidence, cost-effectiveness analysis, and post-marketing safety data standards that investigational peptides do not yet meet

10.1111/apt.15316 33 NiuS.ChenS.ChenX.RenQ.YueL.PanX.et al (2022)

While unpleasant, this side effect is usually temporary and tends to improve as treatment continues