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Those are combinations of GLP-1 and glucagon, triple-hormone receptor agonist, like retatrutide, and there are also oral medications in development for treatment of obesity, either peptides or small molecules

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This 6-step plan in summary: Assess labs and absorption, switch folic acid to active B forms, start low-dose methyl-folate and methylcobalamin with titration, support with protein/choline/B6/magnesium and whole foods, monitor homocysteine and symptoms, and set realistic expectations

People managing diabetes should be especially cautious about medication changes

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