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Neuroscience 303, 4250
Dehydration is a well-established cause of headache and may occur with GLP-1 medications due to reduced fluid intake (from appetite suppression) or increased fluid loss (from gastrointestinal side effects such as nausea, vomiting, or diarrhoea)
Diabet Med 2015;32:30513
This can also be seen after gall bladder removal surgery and I wonder if patients with diarrhea on retatrutide wouldnt benefit from psyllium husk fiber(aka Metamucil in the USA) or taking low doses of drugs called bile acid sequestrants until their GI can adjust to the retatrutide
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