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Description

SIRT1 activation promotes numerous anti-aging effects including enhanced mitochondrial biogenesis, improved stress resistance, reduced inflammation, and activation of cellular quality control mechanisms that remove damaged proteins and organelles

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Published literature describes investigations into pathways such as angiogenesis, the nitric oxide (NO) system, and tissue repair signaling in rodent models (Sikiric et al., 2025, Pharmaceuticals)

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Nle-AngIV also increased spine numbers to 32 spines/50m, but to a lesser extent than Dihexa

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