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Once the patient demonstrates good tolerability, topiramate is added in a low dose, commonly 25 mg at night or 25 mg twice daily, depending on clinical judgment and patient response

TRIUMPH-1 enrolled approximately 2,300 patients and is expected to complete around mid-year

Orforglipron's unrestricted oral dosing and demonstrated superiority over oral semaglutide in ACHIEVE-3 position it as the preferred oral GLP-1 option for many patients

The result people seek: leaner muscle, easier fat loss, faster recovery, deeper sleep, and the kind of vitality that quietly fades with age

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