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much lower at community doses Vomiting up to 36% at high doses Diarrhea 23-26% Constipation 17-19% Fatigue 11-13% Pancreatitis risk trials flagged severe abdominal pain for discontinuation and evaluation Gallbladder issues rapid weight loss increases gallstone risk Thyroid C-cell tumors same boxed warning as semaglutide (animal studies) GI side effects were more intense than semaglutide in trial data due to the dual mechanism
All medications are prescribed based on an individual clinical evaluation by a licensed medical provider
In STEP-1 (N=1,961), 29.7% of participants randomized to semaglutide 2.4 mg reported diarrhea over 68 weeks, compared with 15.9% in the placebo group [4]
Low blood sugar is another context issue
Ongoing support and monitoring is included in Beyond Stem Cells programs
