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10.1074/jbc.M011605200 J
developed an innovative column-switching ion chromatography technique with non-suppressed conductivity detection for the simultaneous determination of L-carnitine, choline, and mineral ions (Wei et al., 2017b)
There, 70% of residents are either overweight or obese
The molecular events leading to activation or silencing of glucose-sensitive neurons are surprisingly similar to those of the endocrine pancreas and include neuronal uptake of glucose via GLUT2, conversion to pyruvate (and finally ATP) via glucokinase, and modulation of neuronal firing mediated by changes in K ATP channel activity, cell depolarisation and Ca 2+ influx
Correcting that single assumption early tends to make every later step, from insurance checks to savings math, far easier to reason through
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