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septic arthritis
3 Oxidative stress Oxidative stress is a disbalance caused by excessive production of prooxidant substances such as ROS and RNS and/or the antioxidant systems working inefficiently ( in vivo primarily by the mitochondrial respiratory chain during aerobic metabolism ( via a reaction between nitric oxide (NO) and superoxide, and nitrosoperoxycarbonate, generated via a reaction between peroxynitrite and carbon dioxide
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To sustain this workload, heart tissue contains the highest concentration of mitochondria (cellular energy factories) of any muscle
Each of these lesions is discussed in more detail elsewhere in this textbook
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