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The mechanism for the observed hypometabolism is still unclear, although we believe that reduced glucose uptake is likely, as in our mouse pilocarpine model hexokinase activity appeared to be unchanged in hippocampus (McDonald et al., 2017)

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Journalist Sara Talpos wrote an excellent expos on peptides in Undark, revealing intriguing facets of peptide-based therapies such as BPC-157, including their history and applications

2-deoxy- d -glucose induces deglycosylation of proinflammatory cytokine receptors and strongly reduces immunological responses in mouse models of inflammation

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