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"The Impact of Omega-3 Fatty Acids on Cellular Uptake Mechanisms: Implications for Nutrient Absorption." Advances in Nutrition Research, 8(2), 123-138

concluded that in physiological conditions, mPTP takes part in Ca 2+ homeostasis by mediating Ca 2+ efflux from the mitochondria 15

Inadequate mitochondrial Asp production is an important cause of T cell dysfunction, and lack of aspartate inhibits nicotinamide purine dinucleotide (NADH) production, causing ER expansion and TNF release