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Why the caveats: Most human data is observational, not randomized controlled trials designed to prove prevents dementia. So far, we cannot definitively say GLP-1 RAs prevent Alzheimers

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doi: 10.1039/D5FB00122F 63

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Thus, changes in these biomarkers do not accurately assess real-time brain function since the underlying and established deficits in neuronal functioning are unaffected by their absence

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Methylcellulose: Bulk-forming laxatives like methylcellulose (Citrucel) can add bulk to stool and facilitate regular bowel movements

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However, reduced side-effects at lower doses make it likely there are also reduced therapeutic effects

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