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The BBB disruption is associated with leakage of blood-derived proteins, including IgG, thrombin, hemoglobin, hemosiderin, and fibrinogen into the parenchyma, and increased IgG, albumin, and complement protein C3a levels in the CSF of ALS patients [46, 240]

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It has been used in clinical trials for ulcerative colitis and multiple sclerosis, and has shown consistent healing effects on various wounds, including skin, muscle, tendon, ligament, bone, and ulcers in the entire gastrointestinal tract

Int J Biol Macromol 98:837846

Fermented foods, which use live microorganisms during production, have a long history of use to improve digestive health, preserve food, and boost nutritional quality