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Recognizing Pancreatitis Symptoms During Tirzepatide Treatment Acute pancreatitis typically announces itself with sudden, severe upper-abdominal pain that radiates to the back, often accompanied by nausea, vomiting, and elevated body temperature

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This was most likely caused by induction of IL-6 after MI (significant correlation between IL-6 and GLP-1 plasma levels was observed)

Macular Edema Another complication associated with Zepbound is macular edema , characterized by fluid buildup in the maculathe central part of the retina responsible for sharp vision