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FIGURE 1 2 Core molecular mechanisms of diabetic kidney disease 2.1 Advanced glycation end products (AGEs) and RAGE activation Advanced glycation end products (AGEs) are a heterogeneous group of molecules formed when reducing sugars, such as glucose, react non-enzymatically with proteins, lipids, or nucleic acids through the Maillard reaction
1 STEER was a retrospective, observational real-world study that evaluated semaglutide versus tirzepatide in lowering the risk of MACE in adult patients with overweight or obesity and established cardiovascular disease with no history of diabetes
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Zepbound : A tirzepatide injection targeting GLP-1 and GIP receptors, proven effective for significant weight loss
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