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The hormone resistin links obesity to diabetes
This was supported in 5xFAD mice, in which exendin-4 treatment alleviated cognitive dysfunction, prevented amyloid- accumulation, and protected mitochondrial function [54]
Combination with other agents might allow dose reduction of the GLP-1 component
Some anecdotal reports suggest it could increase brain excitability
Mounjaro, Ozempic, Rybelsus, Wegovy and Zepbound remain approved by the U.S
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