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They occurred where habitual intake was a fraction of what any US diet delivers, and Keshan disease also appears to require an additional trigger, such as a viral infection
Patients often notice this benefit within the first few weeks, before other changes become visible
In clinical use, significant side effects are uncommon, and the vast majority of patients tolerate the therapy without problems
Ghadimi D, de Vrese M, Heller KJ, Schrezenmeir J (2010) Lactic acid bacteria enhance autophagic ability of mononuclear phagocytes by increasing Th1 autophagy-promoting cytokine (IFN-) and nitric oxide (NO) levels and reducing Th2 autophagy-restraining cytokines (IL-4 and IL-13) in response to Mycobacterium tuberculosis antigen
doi: 10.1152/japplphysiol.00945.2010
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