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One of the most significant of these is the activation of SIRT1, often called a longevity gene. SIRT1 helps manage insulin sensitivity and supports healthier blood sugar regulation, which is fundamental for sustained energy and preventing the metabolic strain that can lead to weight gain
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Most clinicians recommend B12 injections every 1 to 4 weeks for deficiency treatment and once a month for maintenance after deficiency is corrected
[4] Clinical practice typically involves reviewing medication history, assessing liver function, performing a full blood count, and considering haematological or hepatological referral when levels are markedly elevated without clear cause
