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To Issue 159 C itation: Parker M, Lyons S, Lyness A, Scaling GLP-1 Drugs Without a Mountain of Waste
However, while the final outcome of mitochondrial dysfunction is cell death, the phenotype of death (apoptosis and/or necrosis) depends on the level of cellular ATP, as ATP is required for the efficient assembly of the apoptosome
Importantly, women should also avoid alcohol during pregnancy, as per UK Chief Medical Officers' guidance
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These disruptions trigger neuronal malnutrition, structural changes, and functional loss
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