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21, 22 CPAP therapy may be more effective for people with obesity if they are able to lose weight in any healthy, sustainable way
Insulin Resistance While IGF-1 can enhance insulin sensitivity in the short term, chronic exposure to elevated IGF-1 levelsparticularly with IGF-1 LR3 can eventually cause the opposite effect: Downregulation of insulin receptors Impaired glucose uptake Elevated fasting blood sugar levels This risk is amplified when IGF-1 is stacked with HGH , insulin , or consumed with a high-calorie, high-carb diet
It also acts on appetite regulation pathways in the brain, which may support weight reduction as part of comprehensive diabetes management
PLoS ONE 12:e0184764
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