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In FinnGen, the BMI-related GLP-1R proxy was associated with reduced risks of PTSD, ADHD, BD, alcohol dependence, substance abuse, and MDD

Medications may not be as effective if used beyond their expiration date or beyond-use date (BUD) because their strength can decrease over time

Research backs this up: when using GLP-1s to aid in weight loss, they were found to effectively reduce BMI, triglycerides, waist circumference, and total testosterone in people with PCOS, according to a 2024 meta-analysis in the Journal of Diabetes and its Complications

MK-677 (ibutamoren): the long half-life oral drug Spirojopiperidine is an orally active, non-peptide drug

Additionally, it has been tested for other diseases, such as heart and renal diseases