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[1] Strategic timing of your medication can help mitigate these symptoms and improve tolerability

These mechanisms occur within hours after GCs administration and may lead to hyperglycemia, even in individuals without a prior history of glucose abnormalities ( Figure 1 The clinical impact of hyperglycemia during GCs therapy has been well established, with multiple studies reporting increased morbidity and mortality, including higher rates of infection, cardiovascular events and prolonged hospitalisations ( Although glucagon-like peptide-1 receptor agonists (GLP-1 RAs) are not currently recommended in SID by major guidelines, their mechanism of action makes them promising candidates to counteract the metabolic impacts of steroids

And mortality today is half what it was 120 years ago

Meanwhile, Western Asia had a lower incidence (60,715 cases) but still considerable mortality (20,493 deaths)

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